Polyphenols in preventing endothelial dysfunction
نویسندگان
چکیده
منابع مشابه
Tea polyphenols in preventing cardiovascular diseases.
Epidemiological observations suggesting an inverse correlation between tea consumption and the incidence of cardiovascular diseases have been well established [1–4]. The review by Stangl et al. gives an overview of the effects of polyphenolic compounds in tea on the function of the cardiovascular system, especially on various signal transduction pathways in cardiovascular cells [5]. The underly...
متن کاملGeranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction
Radiation-induced intestinal toxicity is common among cancer patients after radiotherapy. Endothelial cell dysfunction is believed to be a critical contributor to radiation tissue injury in the intestine. Geranylgeranylacetone (GGA) has been used to treat peptic ulcers and gastritis. However, the protective capacity of GGA against radiation-induced intestinal injury has not been addressed. Ther...
متن کاملSpecific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
OBJECTIVE Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their antioxidant and anti-inflammatory properties. We investigated whether individual dietary polyphenols representing different polyphenolic classes, namely quercetin (flavonol), (-)-epicatechin (flavan-3-ol), theaflavin (dimeric catechin), se...
متن کاملOpportunity “Nox”: A Novel Approach to Preventing Endothelial Dysfunction in the Context of Insulin Resistance
Cardiovascular complications are more prevalent in individuals with conditions associated with insulin resistance. Knowledge is evolving concerning the mechanistic link between insulin resistance and vascular disease, but complete clarity does not exist. This is a high-priority area of investigation because individual and societal costs associated with diabetic vascular complications are increa...
متن کاملCritical role for CuZn-superoxide dismutase in preventing angiotensin II-induced endothelial dysfunction.
The goal of the present study was to test the hypothesis that the CuZn isoform of superoxide dismutase (CuZnSOD) protects against angiotensin II (Ang II)-induced endothelial dysfunction. Vascular responses of carotid arteries from control, CuZnSOD-deficient (CuZnSOD(+/-)), and CuZnSOD transgenic mice were examined in vitro after overnight incubation with either vehicle or Ang II (1 or 10 nmol/L...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2017
ISSN: 0032-5449,1732-2693
DOI: 10.5604/01.3001.0010.3808